SpatiaBio Pack 3 — Xenium vs Visium Platform Selection Guide
A practical decision framework for spatial transcriptomics platform selection — fact-checked against current manufacturer specs (2026).Choosing between Visium and Xenium isn't about which technology is "better" — it's about which questions you're asking. This guide breaks down the real tradeoffs.### What's inside (11 sections)1. Introduction: Why platform choice matters2. Technical specifications at a glance (Visium v1 / HD / Xenium Prime 5K / CosMx SMI)3. Resolution deep dive — what 2 µm actually means for analysis4. Gene panel tradeoffs: whole transcriptome vs. fixed panel5. Sensitivity and detection efficiency6. Sample compatibility (FFPE, fresh frozen, organoids, aged biobank)7. Cost analysis with break-even calculation8. Bioinformatics pipeline differences (with code)9. Decision framework: 9 experimental scenarios10. Pre-order checklist11. Further reading### Fact-checked, not guessedEvery spec in the comparison table has been checked against current 10x Genomics, Bruker Spatial Biology, and NanoString documentation — including corrections for newer options (Visium HD's 11×11mm capture area, Xenium's actual imageable area, CosMx's expanded gene panels up to 19,000 genes).### Who this is for- Researchers deciding which platform to order before committing reagents- Core facility staff advising PIs on platform selection- Anyone who has been burned by choosing the wrong resolution/panel tradeoff### Format24-page PDF, ready to read — no printing or conversion needed.
Get it → lociven.gumroad.com